HPE Announces NVIDIA-Powered AI Upgrades for Next-Gen Workloads

HPE also unveiled the next generation of HPE Private Cloud AI, co-developed with NVIDIA.

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  • [Image source: Krishna Prasad/MITSMR Middle East]

    Hewlett Packard Enterprise (HPE) has announced major upgrades to its NVIDIA AI Computing by HPE portfolio, aimed at supporting enterprise customers across the entire AI lifecycle. The enhanced offering deepens integration with NVIDIA AI Enterprise and brings the latest NVIDIA AI models and Blueprints to HPE Private Cloud AI, allowing developers to deploy AI applications faster and more easily.

    A key highlight is the introduction of HPE ProLiant Compute servers powered by NVIDIA Blackwell accelerated computing, designed to drive generative, agentic, and physical AI workloads.

    The new line-up includes the HPE ProLiant DL385 Gen11, an air-cooled 2U RTX PRO Server configuration that supports up to two NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs, making it ideal for data centers facing rising AI demands. It also features the HPE ProLiant Compute DL380a Gen12, a 4U configuration capable of supporting up to eight NVIDIA RTX PRO 6000 GPUs, which is set to ship in September.

    These purpose-built servers promise high flexibility and GPU-accelerated performance for workloads spanning robotics, industrial AI, quality control, autonomous vehicles, simulation, 3D modeling, digital twins, and enterprise applications. The Gen12 series also features multi-layered security, quantum-resistant firmware signing, and centralized cloud-native lifecycle automation, potentially reducing IT management time by up to 75% and annual downtime by 4.8 hours per server.

    HPE also unveiled the next generation of HPE Private Cloud AI, co-developed with NVIDIA, which will support the RTX PRO 6000 GPUs, seamless scalability across GPU generations, enterprise multi-tenancy, and air-gapped management. The platform will add support for the latest NVIDIA Nemotron models for agentic AI, Cosmos Reason VLM for robotics, and the NVIDIA Blueprint for Video Search and Summarization (VSS 2.4), allowing enterprises to build video analytics AI agents that can extract insights from massive video datasets.

    Cheri Williams, senior vice president and general manager for private cloud and flex solutions at HPE, said, “HPE is committed to empowering enterprises with the tools they need to succeed in the age of AI. Our collaboration with NVIDIA continues to push the boundaries of innovation, delivering solutions that unlock the value of generative, agentic, and physical AI while addressing the unique demands of enterprise workloads.” 

    He added that with the combination of HPE ProLiant servers and expanded capabilities in HPE Private Cloud AI, they are enabling organizations to embrace the future of AI with confidence and agility.

    Justin Boitano, vice president of enterprise AI at NVIDIA, said, “Enterprises need flexible, efficient infrastructure to keep pace with the demands of modern AI. With NVIDIA RTX PRO 6000 Blackwell GPUs in HPE’s 2U ProLiant servers, enterprises can accelerate virtually every workload on a single, unified, enterprise-ready platform.”

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